Previous studies have shown that the down-regulation of acetyltransferase KAT3B induces apoptosis in renal carcinoma and the variations in the expression levels of MYSTI/MOF/KAT8 may affect the cell cycle and the EGFR signaling pathway (Cocco et al., 2018; Dong et al., 2019). Here, EGFR is linked to renal carcinoma.