Univariate Cox regression analysis indicated that 13 PIMGs had significant association with the survival of BLCA patients in DEIGs (p < 0.01), of which seven genes, including NPR2, TGFB3, PDGFRB, PDGFRA, VIM, RBP1, RBP1 and TNC, increased the risk of prognosis, while the rest, including CD3D, CIITA, GNLY, LCK, PDCD1 and ZAP70, were conducive to survival (Figure 2D). The gene discussed is TNC; the disease is bladder transitional cell carcinoma.