More directly, our findings provided evidence that the expression of DKK1 was correlated with the level of Th1 markers (STAT1 and IFNG) and Th2 markers (GATA3 and STAT6) in various cancers, such as ACC, KICH, MESO, and PAAD (Figure 6; Supplementary Table S1). Here, STAT6 is linked to cancer.