TCF7 and diffuse large B-cell lymphoma: Similarly, a lower T cell exhaustion signature correlated with better CTT efficacy with axicabtagene ciloleucel (axi-cel) and diffuse large B cell lymphoma (DLBCL) in a study by Deng and colleagues (48) and retention of a naïve-like profile with high expression of Tcf7 as well as a low type I IFN profile correlated with better CTT efficacy in ALL in a study by Chen and colleagues (42).