In addition, the peritoneal macrophages from PbANKA-infected mice with α-lactose treatment were able to express higher levels of Gal-9, IFNα, IFNβ, IFNγ, and TREM-1 in comparison of those from malarial mice, suggesting that galectin-receptor interactions play a role in regulating macrophage inflammatory response during the erythrocytic stage of malaria. This evidence concerns the gene LGALS9 and malaria.