Mtb-infection induced cytokine and chemokine production in M1 and M2 and tended to induce tumor necrosis factor (TNF)-α, macrophage inflammatory protein (MIP)-1α,MIP-1β and IP-10 and fractalkine in M1 and M2 (Figure 4A and Supplementary Table 2, n=8). This evidence concerns the gene TNF and infection.