AKT1 and bacterial infectious disease: Indeed, CXCL10 was reported to be a key regulator of the cytokine storm in SARS-CoV-2 infection, CXCL1 to play a role in chemotactic neutrophils in bacterial infections, and OASL to be involved in IFN-gamma signaling and PI3K-Akt signaling pathways, which can restrict virus infection (Stelzer et al., 2016).