Compared to the previously defined nonalcoholic fatty liver disease (NAFLD) criteria, which excluded excessive alcohol consumption or other concomitant liver disease, the characterization of MAFLD introduced a novel algorithm with stratification of patients into categories of overweight or obese, type 2 diabetes mellitus (T2DM), or normal weight/lean with metabolic dysfunction, including central obesity, abnormal glucolipid metabolism profile, and increased hypersensitive C-reactive protein (2). Here, CRP is linked to type 2 diabetes mellitus.