It has been shown that ALT induces apoptosis and triggers cell-cycle arrest in gastric cancer cells through ROS generation and modulation of several ROS-dependent kinase signaling pathways, such as AKT, p38 MAPK, and NF-κB (He W. et al., 2019; He Y. et al., 2019; Zhang and Zhang, 2019). The gene discussed is NFKB1; the disease is gastric cancer.