GPT and leukemia: Recently, the biological activities of ALT against THP-1 leukemia cells have been investigated and the results show that ALT plays an important role in inhibiting cell viability and inducing mitochondrial apoptosis in THP-1 cells by provoking ROS production and interfering in STAT3, survivin, c-Jun, and p38 MAPK signaling pathways (Ahmad et al., 2021).