TUG1 and cancer: Besides other PRC2-associated lncRNAs involved in tumorigenesis and progression, TUG1 regulates the biological behavior and molecular mechanisms of different cancer cells, including cell proliferation, invasion, apoptosis, differentiation, migration, drug resistance, radiation resistance, angiogenesis, mitochondrial bioenergetics, epithelial-mesenchymal transition (EMT), and regulation of blood-tumor barrier permeability among other different cancer cell (Niland et al., 2012; Katsushima et al., 2016; Cai et al., 2017; Chiu et al., 2018).