GAS5 and Hepatic fibrosis: Dong et al. reported that silencing of lncRNA GAS5 increased the expression levels of p-PI3K, p-Akt, and p-mTOR thus revealing that activation of PI3K/Akt/mTOR signaling pathway in liver fibrosis can be mediated by the lncRNA GAS5 (Dong Z. et al., 2019).