NOTCH3 and Hepatic fibrosis: The regulatory role of lncRNAs in liver fibrosis via the Notch signaling pathway was recently reported, and protein and mRNA levels of Notch signaling-related molecules and target genes Notch2, Notch3, and Hes1 were reduced in HSCs with lncRNA LFAR1 downregulation and increased in HSCs with lncRNA LFAR1 overexpression (Zhang K. et al., 2017).