The significance of serum lncRNA GAS5 in the diagnosis of liver fibrosis was proposed by Gou et al. through the detection of abnormalities in lncRNA GAS5 in the serum of patients with chronic hepatitis B, and although the significance of serum lncRNA GAS5 in the age and gender distribution subgroups were not statistically significant (Han et al., 2020). Here, GAS5 is linked to Hepatic fibrosis.