Studies have reported that Hippo (MST)-YAP signaling is involved in brain vessel in various diseases, including cerebral I/R injury and subarachnoid hemorrhage, suggesting the potential for the modulation of this signaling pathway to influence the prognosis of many types of neurological disorders (Gong et al., 2019; Zhao et al., 2016; Qu et al., 2018). Here, YAP1 is linked to subarachnoid hemorrhage.