In our previous studies, we found that tau concentrations correlate significantly with postconcussive, post-traumatic, and depressive symptoms (Kenney et al., 2018; Pattinson et al., 2020) and exosomal NfL positively correlated with chronic postconcussive symptoms, PTSD, and depressive symptoms in predominantly male TBI groups (Guedes et al., 2020). The gene discussed is NEFL; the disease is post-traumatic stress disorder.