Increasing evidence has shown that CKI can be used to halt cancer migration (Nourmohammadi et al., 2019), reduce anticancer drug resistance (Hy et al., 2014), increase cancer cell apoptosis (Qu et al., 2016), suppress the cancer cell cycle (Cui et al., 2019), and inhibit cancer progression (Wang et al., 2019). The gene discussed is CHKA; the disease is cancer.