CKI is widely being used in the treatment of cancers, such as breast cancer (Xu et al., 2011a; Qu et al., 2016; Cui et al., 2019; Nourmohammadi et al., 2019; Cui et al., 2020), acute myeloid leukemia (Jin et al., 2018), and hepatocellular carcinoma (Gao et al., 2018; Yang et al., 2021). The gene discussed is CHKA; the disease is cancer.