MAPT and neurodegenerative disease: Similar pattern of regional tau deposition in these MTL regions without amyloid-β pathology has been observed in other neurodegenerative diseases including argyrophilic grain disease (Ferrer et al., 2008) and primary age-related tauopathy (Crary et al., 2014), where tau pathology is related to structural changes in the anterior hippocampus (Josephs et al., 2017).