SV2C and Alzheimer disease: Consistent with these studies, the expression levels of Sv2C in AD model and AD_Pls cells were 3.88- and 3.36-folds higher than that of the controls, and the NPY2R levels were up-regulated by 8.78- and 6.98-folds in AD and AD_Pls groups when compared with the controls (Supplementary Table 2).