AntagoNATs effectively increased the expression of brain-derived neurotrophic factor (BDNF), a protein important in memory development (Modarresi et al., 2012), and the healthy allele of SCN1A, the haploinsufficiency of which triggers Dravet syndrome (Hsiao et al., 2016). This evidence concerns the gene SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.