In AD pathology, SNHG1 involves in Aβ-induced neuronal injury via two different ceRNA regulatory axes, SNHG1/miR-137/kringle containing transmembrane protein 1 (KREMEN1) (Wang et al., 2019) and SNHG1/miR-361-3p/zinc finger gene 217 (ZNF217) (Gao et al., 2020). This evidence concerns the gene KREMEN1 and Alzheimer disease.