Expression of epilepsy mutant Kv7.2 (R207W) (Figure 3A) along with Kv7.3 produced smaller currents with slower voltage-dependent activation profile [Figures 3B–E, activation constants 1,006 ms (R207W) vs. 104 ms (WT)], in agreement with previous reports (Dedek et al., 2001). This evidence concerns the gene KCNQ2 and epilepsy.