CD40LG and infection: Similar to results observed on day 5 p.i., CD40L-/- mice upon infection did not show a significant increase in the numbers of peripherally derived monocytes/macrophages (CD45hiCD11b+ Ly6G-) and brain resident microglia (CD45loCD11b+) compared to the respective MI (as shown in the graph in Fig 5B) on day 10 p.i. but WT mice showed increased numbers of both the cell populations.