COBL and ischemic stroke: Taken together, the levels of the actin nucleator Cobl are responsive to MCAO-induced brain damage, and Cobl is critically needed for an acute process of dendritic regrowth and branching that is triggered by ischemic stroke conditions and is powerful enough to fully repair the strong defects in dendritic arborization, which we observed as consequences of ischemic stroke in the cortex.