SFRP2 and colorectal carcinoma: The methylation status of other genes, including BMP3, SDC2, PHACTR3, SPG20, TFPI2, TMEFF2, KRAS, HPP1, SFRP2, MGMT, and WIF1, have also been investigated in fecal DNA for early detection of CRC [17,96,97,98,100].