Other CD5/CD10-double negative low-grade B cell lymphomas may very infrequently show aberrant expression of CD10, posing a diagnostic challenge to differentiate from FL (particularly with splenic presentation), as covered extensively elsewhere and in this review series [42,43,44,45,46] (and cross referencing Auerbach, Gomes and Aggarwal’s papers). This evidence concerns the gene CD5 and B-cell non-Hodgkin lymphoma.