PART1 and head and neck squamous cell carcinoma: By contrast, in the context of HNSCC, bioinformatics findings in tongue squamous cell carcinoma (TSCC) supported the tumor suppressive role of PART1, demonstrating that PART1 was downregulated in TSCC tissues and that high expression levels of PART1 were associated with a prolonged overall survival of TSCC patients [48,49].