Previous studies have found that during the occurrence of AKI, cell apoptosis is related to inflammation, and inflammation produces a large amount of inflammatory factors such as TNF-α, IL-6, IL-1, etc. These inflammatory factors can be used as the initiating factors of apoptosis and activate the apoptosis pathway, thereby mediating the death of renal tubular cells [20]. The gene discussed is TNF; the disease is acute kidney injury.