METTL1 and hepatocellular carcinoma: Our data revealed that knockdown of METTL1 in HCC cell lines Huh7 and MHCC97H resulted in decreased m7G tRNA modifications (Figure 2A, B and Figure S3A‐C), and inhibited the growth (Figure 2C and Figure S3D), colony formation (Figure 2D and Figure S3E), cell cycle progression (Figure 2F and Figure S3F), migration and invasion capacities (Figure 2G, H and Figure S3H, I) in both Huh7 and MHCC97H cells.