Increased naive and memory B cell, resting memory CD4+ T cell, follicular helper T (Tfh) cell, monocyte, resting natural killing (NK) cell, M0 and M1 macrophage, resting mast cell, and activated mast cell infiltration suggests significant immune regulation in the cancer microenvironment, which offers more options for immunotherapy and more targets for sensitivity assessment [34–36]. Here, CD4 is linked to cancer.