We searched for genes involved in 8 common pathways (NF-κB signaling pathway, PI3K/Akt signaling pathway, MAPK signaling pathway, JAK/STAT signaling pathway, TGFβ/SMAD signaling pathway, Wnt/β-catenin signaling pathway, Notch signaling pathway, Hedgehog signaling pathway) in the PathCards database and queried the expression of these genes in glioma by analyzing data from the GEPIA database. This evidence concerns the gene NFKB1 and central nervous system cancer.