KRAS and colorectal carcinoma: As well as our recent study re-sensitising Kras-mutant CRCs to rapamycin by targeting translation initiation (Knight et al., 2020a), we have demonstrated that Kras-mutant models of CRC depend upon the transporter SLC7A5 to maintain protein synthesis by facilitating the influx of amino acids (Najumudeen et al., 2021).