While the role of NLRP2 is not specifically characterized in SARS-CoV-2 infection, NLRP2 has shown sex-biased expression in influenza infection [63], and another member of the same NOD-like receptor family, NLRP3, is involved in inducing pulmonary inflammation in COVID-19 [64]. The gene discussed is NLRP3; the disease is COVID-19.