Moreover, indicated in the same database, of these seven genes, variants in four of them (SAMD4A, IGF2BP3, PIP4K2A, and BMP15) and additionally HDAC4 have been associated with abnormal body height as is often observed in patients with FBN1 mutations (tall MFS patients or short stature acromelic dysplasia patients [78, 79]. Here, IGF2BP3 is linked to acromelic dysplasia.