Tumor cells in all 20 cases were strongly positive for CD3 (Fig. 2 A, E) and CD7, while CD2(19/20), CD43(19/20), CD8(17/20) (Fig. 2 C, G), and CD56(15/20) (Fig. 2D, H) were positive for partial tumor cells. The gene discussed is SPN; the disease is neoplasm.