Statistic analysis of the 140 BLCA samples revealed that ATF5 expressions were associated with clinical grade (P = 0.034), stage (P = 0.014), tumor multiplicity (P = 0.004), recurrence (P = 0.022) as well as progression (P = 0.016), however, they were not correlated with gender, tumor size or age (Table 4). The gene discussed is ATF5; the disease is bladder transitional cell carcinoma.