In the present study, comparing the expression levels of 35 mentioned genes in KD compared to other symptomatically like diseases mainly infections of bacterial or viral causes, juvenile idiopathic arthritis, Henoch-Schönlein purpura, infection of unknown etiology, group A streptococcal and adenoviral infections, and incomplete KD, we revealed two upregulated genes including CR1 and CASP5 in samples of patients with KD compared to other. The gene discussed is CR1; the disease is juvenile idiopathic arthritis.