IL6 and metabolic disease: In case of CD, as the pro-inflammatory markers like IL-6 are already present, the pre-existing autoimmune reaction may help to curb the proliferation of SARS-CoV-2 virus when the CD patients are contacted with the SARS-CoV-2 virus, makes the COVID-19 cases of CD patients to be mild if the CD patients do not have metabolic disorders like obesity or diabetes mellitus.