The level of pancreatic tissue necrosis and the expression of M1 macrophage marker F4/80 in the AP+CLDL group were lesser when in comparison with the AP group and AP+Lip group, and the expression of iNOS, TNF-α, IL-6, and IL-1β in the AP+CLDL group was lower than that in the AP group and AP+Lip. This evidence concerns the gene NOS2 and alkaline phosphatase measurement.