On the other hand, CXCR3 chemokine receptors may also be essential for allowing the migration of DCs infected with HSV-2 to lymph nodes, as CXCR3−/- mice showed a significant decrease in the number of both cDCs (B2020-CD11c+) and pDCs (B220+CD11c+) being mobilized to draining lymph nodes in a genital HSV-2 infection model 3 days post-infection [170]. The gene discussed is ITGAX; the disease is infection.