The levels of E-cadherin, Vimentin, IL-33 and ki67 in GC tissues were further analyzed by IHC, which corroborated that the positive rates of Vimentin, IL-33 and Ki67 in GC tissues were heightened and the positive rate of E-cadherin was declined in the CAFs group versus the NC group. This evidence concerns the gene IL33 and gastric cancer.