In addition, SNHG16/miR-30a/RRM2 axis also accelerates breast cancer cell proliferation and promote cell invasion [32], while miR-30a regulates liver cell proliferation and apoptosis through the suppressor of cytokine signaling 1 (SOCS-1)/JAK/STAT signaling pathway in rats with sepsis [33]. The gene discussed is RRM2; the disease is breast carcinoma.