GDI2 and neoplasm: To elucidate whether GDI2 was positively correlated with HCC occurrence, the GDI2 expressions were compared between 371 HCC cases and 50 normal tissue cases via RNAseq TMP data from TCGA combined with GTEx, which showed much higher expression of GDI2 in tumor cases than in normal cases (P < 0.001, Figure 1A).