GDI2 and neoplasm: In view of the immune infiltration analysis that GDI2 expression was utmost positively correlated with T helper cells but utmost negatively with plasmacytoid Dendritic cells (pDC) (Figure 3), it could be speculated that GDI2 might play an role in immune tumor microenvironment for HCC progression, which definitely requires profound and comprehensive researches for further confirmation.