GDI2 and cholangiocarcinoma: It was shown that GDI2 significantly expressed in most of the 33 kinds of solid tumors, such as hepatocellular carcinoma (LIHC, HCC), lung adenocarcinoma (LUAD), cholangiocarcinoma (CHOL), breast cancer (BRCA), glioblastoma (GBM), endometrial carcinoma of uterus (UCEC), etc (Figure 1C).