The gene set variation analysis (GSVA) analysis indicated that some cancer‐related hallmarks and pathways varied among the IMPs, as shown in the heatmaps of GSVA enrichment scores such as: apoptosis, Notch signaling and KRAS signaling, and immune biological processes including interleukins‐, interferons‐, TNFα‐ and TNFβ‐signaling, CD4+ αβT cells activation, DCs chemotaxis and leukocytes mediated cytotoxicity, and PD‐1 signaling pathways (Table S3 and Fig. 1F). The gene discussed is CD4; the disease is cancer.