The results demonstrated that deficiency of ADAMDEC1 promoted gastric cancer cell proliferation and migration as presented in Fig. 6B, C. Interestingly, PD-L1 mRNA and expression levels were both upregulated following with depletion of ADAMDEC1 in MGC803 cell line (Fig. 6D, E). The gene discussed is ADAMDEC1; the disease is gastric cancer.