TMPRSS2 and cancer: Enrichment analysis was performed using HUGO symbols of genes recurrently hit per dataset, indicating that the pathway “Transcriptional misregulation in cancer [KEGG:05202]” was significantly more frequently hit (P = 1.6 × 10−4) within PCa due to TMPRSS2, ERG, ETV1, H3FA3, SLC45A3, and ELK4.