The large number of PCa samples allowed TMPRSS2-ERG to be analysed in-depth, revealing additional cryptic and intergenic exons including TMPRSS2 exon 0 [40], a detailed map of the genomic breakpoints, genomic breakpoints located before ERG that combined with cryptic intergenic exons co-exist with exon 2 deletions, and a tumour that harbours TMPRSS2-ERG that originated from a reciprocal translocation rather than a deletion. The gene discussed is TMPRSS2; the disease is posterior cortical atrophy.