In addition to improved liver macrophage infiltration and M1 macrophage polarization was also quantified based on levels of hepatic macrophage infiltration density in steatosis area, strong CD11b, CD11c, and CCR7 staining and protein levels were observed central tracks and steatosis area in the liver of ob/ob mice (Figure 8A,B). The gene discussed is ITGAX; the disease is steatosis.