AREG and breast carcinoma: Similarly, the rs3750817-related gene FGFR2 (HGNC:3689) [64,65,66,67,68,69,70,71], the rs1092913-related gene ROPN1L (HGNC:24060), the rs10822013-related gene ZNF365 (HGNC:18194) and the rs62314947-related gene AREG (HGNC:651) also exhibited association with poor relapse-free survival in breast cancer patients with lower gene expression (Figure 4D–G).