MEN1 and breast carcinoma: In this Dutch survey, MEN1 patients had a median age at diagnosis of breast cancer of 45 years old, compared with 57.5 years old in female relatives without MEN1, and 61.2 years old in the Dutch sample population, suggesting the need for early screening of this condition in MEN1 female patients.[19] Although we recognize it would be interesting to test this patient breast cancer tissue for somatic events in the MEN1 gene, unfortunately, this is not possible because the patient had undergone surgery many years ago at another institution.