Besides markers examined, there are also other recently proposed candidate substances such as cytokines (IL-6, IL-8, IL-17) that are indicative to have high clinical diagnosis and prognosis value as biomarkers of gastric cancer.[27–30] With the increase in the typys of detected markers, the establishment of a combined detection and prediction model for patients with gastric cancer will be very necessary in the future. This evidence concerns the gene IL6 and gastric cancer.