MAPK1 and stroke disorder: Studies have shown that CAMP is closely related to axonal regeneration after stroke.[32] As a member of the gene-encoding MAP kinase family, MAPK1 integrates a variety of biochemical signals and participates in a variety of cellular processes, such as proliferation, differentiation, transcriptional regulation, and development.[33] The protein encoded by the TP53 gene responds to a variety of cellular stresses to regulate the expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or metabolic changes.