Studies have shown that CAMP is closely related to axonal regeneration after stroke.[32] As a member of the gene-encoding MAP kinase family, MAPK1 integrates a variety of biochemical signals and participates in a variety of cellular processes, such as proliferation, differentiation, transcriptional regulation, and development.[33] The protein encoded by the TP53 gene responds to a variety of cellular stresses to regulate the expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or metabolic changes. This evidence concerns the gene CAMP and stroke disorder.