Indeed, panobinostat increased the expression of HDAC6 [Figure 5D] in both SUDHL4 (a diffuse large B-cell lymphoma cell line) and Daudi (a Burkitt lymphoma cell line), suggesting the HDAC6 upregulation by panobinostat is applicable to both myeloma and lymphoma models. The gene discussed is HDAC6; the disease is diffuse large B-cell lymphoma.