TP53 and cancer: Even though for 9 common cancer driver genes (TP53, ESR1, GATA3, KMT2C, NCOR1, AKT1, NF1, RIC8A and RB1), no further enrichment was observed in metastatic TNBC when compared to early TNBC, and increased TMB and clonal diversity were observed in metastatic TNBC.