An IL-15 and CCL20 (chemokine)-armed oncolytic adenovirus (CRAd-CCL20-IL15) in combination with cytotoxic effector (combination of T cells and NK cells) adoptive therapy showed greater anti-tumour efficacy compared to cytotoxic effector cells or CRAd-CCL20-IL15 alone against colon tumours in a murine model[102]. Here, CCL20 is linked to colonic neoplasm.