For instance, a lipid-rich tumor microenvironment favours expansion of the pro-tumoral, interleukin (IL)-17 secreting γδ T cell subset over the anti-tumoral interferon (IFN)γ producing γδ T cells (Lopes et al., 2021), and since glycolysis controls the translation of IFNγ-mRNA, the lack of glucose impairs T cell cytokine production (Chang et al., 2013). This evidence concerns the gene IFNG and neoplasm.